Minute Virus of Mice (MVM) is among the most common model viruses utilized as a spiking agent during viral clearance validation. MockV has engineered a non-infectious MVM-Mock Virus Particle (MVM-MVP) that will enable scientists to accurately and economically predict MVM clearance throughout process development, prior to expensive validation studies. According to published data1, our MVM-MVP demonstrates a similar hydrodynamic radii, surface charge and hydrophobicity profile to live MVM. A BSL-1 compatible MVM-MVP Kit is available for testing. This prototype includes a highly purified and concentrated stock solution of MVM-MVP for use as a “spiking agent” and quantification reagents to conduct a sensitive and specific Immuno-qPCR assay.
1 Johnson, S., Brorson, K.A., Frey, D.D. et al. Appl Biochem Biotechnol (2017) 183: 318. https://doi.org/10.1007/s12010-017-2447-y
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